Endocrine Abstracts

31 years old lady with no past medical history or family history of thyroid disease had her first dose of Pfizer vaccine and few days later she presented unwell, Febrile with painful swelling in the neck. She was thought to have Covid because of fever. Examination revealed tender thyroid enlargement with positive bruit and Tachycardia. Investigations showed florid thyrotoxicosis with TSH: < 0.02, fT4: 60.0, CRP: 60, rest of investigation: normal, TRab and TPO AB: pending, ...

61-year-old previously fit and healthy female presented with one-week history of confusion and altered consciousness. There was no history of fever, headache or limb weakness. She was dehydrated, Glasgow Coma Scale score was 11/15, pupils were equal and reactive to light bilaterally and rest of examination was unremarkable. Initial investigations are outlines in Table 1. X-ray-chest showed mediastinal lymphadenopathy and CT head was unremarkable. She was initially treated for ...

Purpose: To compare effectiveness of different radioiodine activities used for the treatment of benign thyroid disease.Method: We retrospectively reviewed our local radioiodine audit data collected over 7 years duration. Patients with benign thyroid disease and known post-treatment biochemical outcomes were included. Data were analysed for primary diagnosis, activity dose, and biochemical outcomes in 6 and 12 months post-treatment....

Graves disease is an autoimmune disorder of the thyroid gland. It is a very rare condition that a Graves patient presents with spontaneous hypothyroidism. Hypothyroidism during the course of Graves’ disease occurs commonly due to radio-iodine (RAI) therapy or thyroidectomy. It may also develop after anti-thyroid drug (ATD) treatment. We present a case of 44 years old Emarati male heavy smoker diagnosed with graves’ disease after thyrotoxic manifestations, associated ...

Background: Hyponatremia is associated with increased, inpatient mortality and length of stay and correct management necessitates doing appropriate investigations for accurate diagnosis of the cause.Aim: The aim of this audit was to identify, the number of medical and surgical patients admitted with hyponatreima over a 4-week period; number of cases with mild (<135) vs moderate to severe cases of hyponatremia (<130 mmol/l); determine if hyponatre...

Introduction: Primary hyperparathyroidism (PHPT) is the most common cause of hypercalcemia, often caused by a single adenoma (85%) or four-gland hyperplasia (15%). Brown tumors are rare erosive bony lesions caused by localised rapid osteoclastic turnover resulting from hyperparathyroidism.Case presentation: A 28-year-old lady presented to the Emergency Department with a 3-day history of fever, dry cough and generalized body aches. She reported sudden ons...

Introduction: Generously supported by IPSEN)-->Insulin tolerance test (ITT) is considered as the gold standard assessment for hypothalamic–pituitary–adrenal axis (HPA) integrity. Short synacthen test (SST) is a relatively simple, low-cost and well tolerated first line test of HPA despite concerns regarding accuracy. The glucagon stimulation test (GST) is often used as an alternative to the ITT. Although less reliable, it is...

Background: The exact changes of hormones and the relative importance of these to the metabolic improvement after bariatric surgery remain to be explored. We highlight the unusual case of a patient who developed episodes of angioedema post roux-en-y surgery for weight reduction.Case: A 38-year-old man with a BMI of 50 kg/m2, had laparoscopic Roux-en-y bypass surgery, resulting in 89 kg loss over 12–18 months. Six to twelve 12 months post-...

Introduction: Carcinoid tumours commonly originate from the gastrointestinal tract. Cardiac manifestations occur in 10–41% of patients with carcinoid syndrome, usually associated with liver metastases. We report an atypical case of a carcinoid tumour associated with right sided heart disease without distant metastases.Case description: A 75-year-old lady with no significant past medical history and a lifelong non-smoker, was admitted with 3 months h...

A 55-year-old gentleman was referred to surgeons for screening colonoscopy in view of family history of bowel cancer. His mother, maternal aunt and two cousins had history of bowel cancer. When seen by the surgeons, he gave 4-month history of intermittent abdominal bloating and rectal bleeding. His past medical history included a recent diagnosis of hypertension, a chronic history of facial neuralgia and history of excision of numerous facial skin tags. He was on amlodipine 5 ...